• Kandlakunta, Praneeth, Richard Pham, Tiezhi ZhangDevelopment of multi-pixel x-ray source using oxide coated cathodes. Physics in Medicine and Biology, 2017, in press.
  • Tiezhi Zhang*, Ovidiu Marina, Peter Chen, Melanie Teahan, Qiang Liu, Lisa Benedetti, A three-field monoisocentric inverse breast treatment planning technique without half-beam blocking. Journal of Clinical Medical Physics, 2015, 16(5):5494
  • Joshua Kim, Weiguo Lu, Tiezhi Zhang*, Dual source dual detector Tetrahedron Beam Computed Tomography for Image guided radiotherapy. Physics in Medicine and Biology, 2014, 59(3):615-30.
  • Joshua Kim, Haiqun Guan, David Gersten, Tiezhi Zhang*, Evaluation of algebraic Iterative image reconstruction methods for Tetrahedron Beam Computed Tomography systems. Int J. Biomed Imaging, 2013: 609704. PMID: 23781236.
  • Joshua Kim, Dan Ionascu, Tiezhi Zhang*, Algebraic Iterative Image Reconstruction using a cylindrical image grid For Tetrahedron Beam Computed Tomography.  Medical Physics, 2013, 40(8):081909, PMID: 23927323.
  • Xiaochao Xu, Joshua Kim, Philip Laganis, Derek Schulze,Yongguang Liang and Tiezhi Zhang*A Tetrahedron Beam Computed Tomography Benchtop System with a Multiple Pixel Field Emission X-Ray Tube. Medical Physics, 2011, 38(10): 5500-5508. PMID: 21992368.
  • Derek Schulze, Jian Liang, Di Yan and Tiezhi Zhang*Comparison of Various Online IGRT Strategies: The Benefits of Online Treatment Plan Re-optimization. Radiotherapy and Oncology, 2009, 90(3): 367-76. PMID: 18976828
  • Tiezhi Zhang* Derek Schulze, Xiaochao Xu and Joshua Kim, Tetrahedron Beam Computed Tomography (TBCT): A New Online Imaging System for Image Guided Radiotherapy. Physics in Medicine and Biology, 2009, 54(11): 3365-78. PMID: 19430106
  • Tiezhi Zhang*, Yuwei Chi, Elisa Meldolesi and Di Yan. “Automatic Delineation of Online Head and Neck CT Images: Towards Online Adaptive Radiotherapy”, International Journal of Radiation Oncology, Biology and Physics, 2007, 68(2), 522-530. PMID: 17418960.
  • Tiezhi Zhang*, Weiguo Lu, et al. Breathing Synchronized Delivery (BSD): A Potential Four dimensional tomotherapy Technique. International Journal Of Radiation Oncology, Biology and Physics, 2007, 68(5):1572-8. PMID: 17570608
  • Dinesh Tewatia, Tiezhi Zhang*, Wolfgang Tome, Bhudatt Paliwal, Minesh Mehta, Clinical implementation of target tracking by breathing synchronized delivery. Medical Physics Journal, 2006, 33(11): 4330-4336. PMID: 17153412.
  • Tiezhi Zhang*, Nigel Orton, Wolfgang Tomé, On the automated definition of mobile target volumes from 4D-CT images for stereotactic body radiotherapy. Medical Physics Journal, 2005, 32(11): 3493-3502. PMID: 16370433
  • Tiezhi Zhang*, Nigel Orton, Thomas Mackie, Bhudatt Paliwal, Technical note: A novel boundary condition using contact elements for finite element based deformable image registration. Medical Physics Journal, 2004 31(8): 2412-2415. PMID: 15487720
  • Tiezhi Zhang*, Robert Jeraj, Harry Keller, Weiguo Lu, Gustavo H. Olivera, Todd R. McNutt, Tomas R. Mackie, Bhudatt Paliwal, Treatment plan optimization incorporating respiratory motion. Medical Physics, 2004 31(6): 1576-1586. PMID: 15259662
  • Tiezhi Zhang*, Harry Keller, Matthew O’Brien, Thomas Mackie, Bhudatt Paliwal, Application of the spirometer in respiratory gated radiotherapy. Medical Physics, 2003 30(12):3165-3172. PMID: 14713083
  • T Zhao*, B Sun B, K Grantham, L Rankine, B Cai, SM Goddu, L Santanam, N Knutson, T Zhang, M Reilly, B Bottani, J Bradley, S Mutic, E Klein, Commissioning and initial experience with the first clinical gantry-mounted proton therapy system. J Appl Clin Med Phys. 2016 Mar 8;17(2):5868.
  • L Zhuang, J Liang, D Yan, T Zhang, O Marina, D. Ionascu*, An optimization algorithm for 3D real-time lung tumor tracking during arc therapy using kV projection images. Med Phys. 2013, 40(10):101710, PMID: 24089900.
  • GD Hugo*, J Campbell, T Zhang, D Yan, Cumulative Lung Dose for Several Motion Management Strategies as a Function of Pretreatment Patient Parameters. International Journal of Radiation Oncology, Biology and Physics, 2009, 74(2):593-601. PMID: 19327911
  • Kristy Brock* and Deformable Registration Accuracy Consortium, Results of A Multi-Institution Deformable Registration Accuracy Study. International Journal Of Radiation Oncology, Biology and Physics, 2010, 76(2): 583:596. PMID: 19910137.
  • Manon RR*, Jaradat H, Patel R, Zhang T, Fenwick J, Tome W, Fowler J, Paliwal B, Soisson E, Yuan Z, Mehta M, Potential for radiation therapy technology innovations to permit dose escalation for non-small-cell lung cancer. Clin Lung Cancer. 2005 Sep;7(2):107-13. PMID: 16179097

*Denotes corresponding/senior authorship.


  • Tiezhi Zhang, Harry Keller, Bhudatt Paliwal. A spirometer-laser combined respiratory motion tracking system. S. Patent #7,367,955. Institution owned.
  • Tiezhi Zhang, Bhudatt Paliwal. Apparatus and method using synchronized breathing to treat tissue subject to respiratory motion. S. Patent # 7,778,691. Institution owned.
  • Tiezhi Zhang, Scanning slot cone-beam computed tomography and scanning focus spot cone-beam computed tomography.
  • Tiezhi Zhang, Tetrahedron beam computed tomography. Patent #7,760,849. Institution owned.
  • Tiezhi Zhang, Xiaochao Xu, Joshua Kim, Di Yan, Alvaro Martinez, Tetrahedron beam computed tomography with multiple detectors. Granted.
  • Tiezhi Zhang, Joshua Kim, Dual source dual detector tetrahedron beam computed tomography for image guided radiotherapy. US Patent Granted.
  • Tiezhi Zhang, Sasa Mutic, A novel Linac design optimized for 4pi delivery. US patent filed.
  • Tiezhi Zhang, Multi-pixel x-ray source. Provisional patent filed.

Selected conference abstracts (recent years)

2017 AAPM Annual Conference

  1. Oral and BEST in PHYSICS (therapy): Highly Efficient Linac Design Optimized for 4pi Radiotherapy:  Tiezhi Zhang, Weiguo Lu, Rao Khan, Sasa Mutic
  2. Poster: Craniospinal Irradiation Using a Precise Geometric Matching Planning “Technique with Dual Scattered Protons:  Francisco J. Reynoso, Tianyu Zhao, Baozhou Sun, Sreekrishna M. Goddu, Lakshmi Santanam, Sasa Mutic, Tiezhi Zhang.
  3. Snap oral:  Development and Evaluation of Iterative CT Image Reconstruction in Cylindrical Image Coordinate:  Wei Rao, Richard Pham, Praneeth Kandlakunta, Mark Anastasio and Tiezhi Zhang.
  4. Oral: Joint Image Domain Motion-Estimation and Motion-Compensation for 4D Cone Beam Computed Tomography Image Reconstruction: Richard Pham,  Wei Rao, Praneeth Kandlakunta, Deshan Yang, Mark Anastasio, Tiezhi Zhang
  5. e-Poster: Non-Coplanar Helical Arc Radiation Therapy (NCHART):  Mingli Chen, Tiezhi Zhang, Steve Jiang, Weiguo Lu
  6. SAM session: Tetrahedron Beam Computed Tomography Based On Multi-Pixel X-Ray Source and Its Application in IGRT:  Invited Presentation – Session:  Non-Conventional Multisource X-Ray Imaging:  Cardiac, Breast Imaging and Cone Beam CT:  Tiezhi Zhang, Otto Zhou, Michael Speidel, S Hsieh
  7. Snap oral: Thermal Analysis of a Stationary Target of X-Ray Sources Operating in Pulse Mode:  Praneeth Kandlakunta, Richard Pham, Wei Rao, Rao Khan, Tiezhi Zhang

2016 AAPM Annual Conference

  1. Oral and BEST in PHYSICS (imaging): Developement fo High Brightness Multiple Pixel X-ray Source Using Oxide Coated Cathodes Praneeth Kandlakunta, Richard Pham and Tiezhi Zhang
  2. Poster, Development of Dose-Based Image Guided Proton Therapy Workflow, Richard Pham, et al.